Investigators probing the disappearance of Nancy Guthrie, the mother of television host Savannah Guthrie, say newly uncovered evidence points to a deeply troubling possibility: she may have been abducted from her bed during the night.
Law enforcement officials briefed on the case revealed that forensic teams discovered blood stains inside the bedroom during an intensive examination of the home. While authorities stressed that the amount of blood found was limited, they described the discovery as significant enough to trigger immediate laboratory testing.
On Wednesday, investigators confirmed that DNA analysis identified the blood as belonging to Nancy Guthrie herself, ruling out the presence of another unidentified individual at the scene. Officials declined to publicly speculate on how the blood was shed, but noted that its location and pattern were “inconsistent with an accidental injury.”
“These findings indicate that Ms. Guthrie was likely in her bed at the time something occurred,” a law enforcement source said. “The evidence suggests she did not leave the home under normal circumstances.”
Police emphasized that the investigation remains active and ongoing, and that no suspects have been formally named. Authorities also cautioned that while the evidence raises the strong possibility of an overnight abduction, final conclusions have not yet been reached.
The Pima County Sheriff’s Department has declined to release further details at this stage, citing the sensitivity and evolving nature of the case. Meanwhile, the Guthrie family has requested privacy as they process the latest and most unsettling developments.
Friends close to the family described the update as “devastating,” saying that while hope remains, fear has intensified as more evidence emerges. Investigators continue to urge anyone with information — no matter how small — to come forward, stressing that even minor details could prove crucial in understanding what happened during the critical overnight hours when Nancy Guthrie vanished.

